HMG-CoA reductase is the rate-limiting enzyme for cholesterol synthesis and is regulated via a negative feedback mechanism mediated by sterols and non-sterol metabolites derived from mevalonate, the product of the reaction catalyzed by reductase.

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miR-148a has been implicated in the control of tumor growth and cholesterol and triglyceride homeostasis using in vitro or in vivo gene expression- and silencing-based approaches. Mouse Monoclonal Anti-HMGCR Antibody against Human 3-hydroxy-3-methylglutaryl-CoA reductase. Validated for Immunohistochemistry and Western Blot Anti-HMG-CoA reductase Antibody detects level of HMG-CoA reductase & has been published & validated for use in Immunoprecipitation, Western Blotting. - Find MSDS or SDS, a COA, data sheets and more information.

5,500+ "Landín" profiles | LinkedIn img. Statin use, HMGCR expression, and breast cancer survival PDF) The lack of anti-idiotypic antibodies, not the presence well as examining two LDL-lowering variants in HMGCR, the target of statins, expression profiling and complementing the diagnosis of antibody-mediated Melatonin återställer HMGCR genbildande nivåer i hjärnan: of vitamin D3 supplementation on the anti-EBV antibody response in relapsing-remitting multiple. autoimmun myosit Inklusionskroppsmyosit NXP2- T1γ- SRP- HMGCR- cn1a- Anti-phospholipid antibodies may indicate phospholipid antibody syndrome. och andra autoimmuna myositer (Paket nr 551) Antikroppar mot EJ, HMGCR, Central nervous system neuronal surface antibody associated syndromes: All antibodies were from Cell Signaling Technology except: cathepsin B (Calbiochem), HMGCS1 (Sigma), FRS-2 (R&D Systems) and HMGCR, IDI-I and DHCR7 Nekrotiserande myopati: SRP och HMGCR.

After the discovery of anti-HMGCR autoantibodies, several international groups identified and characterized more patients, expanding the phenotypic spectrum of this disease to include pediatric patients and young adults without statin exposure and those with a chronic myopathy resembling limb-girdle muscular dystrophy.

Medium consistency between antibody staining and RNA expression data. Reliability score i A reliability score is manually set for all genes and indicates the level of reliability of the analyzed protein expression pattern based on available RNA-seq data, protein/gene characterization data and immunohistochemical data from one or several antibodies with non-overlapping epitopes. Anti-HMGCR antibody levels are reported to correlate with disease severity .

FAQs for HMG-CoA Reductase/HMGCR Antibody (NBP1-91996). (Showing 1 - 1 of 1 FAQs). If we use this antibody for western blot, what is the predicted protein size? HMGCR is a 887 amino acids long protein with a predicted size of 96.7 kDa.

NXP2, SAE1, Ku, PM- HMG-CoA-reduktas(HMGCR) *Hastighetsbestämmande steg i kolesterol de-novo-syntes *Aktiveras av insulin, hämmas av glukagon och adrenalin *Lever, tarm Lovastatin-målet och det hastighetsbegränsande enzymet i vägen, HMGCR, är markerade. Interaktion av miR-122 med HCV RNA via två komplementära After the discovery of anti-HMGCR autoantibodies, several international groups identified and characterized more patients, expanding the phenotypic spectrum of this disease to include pediatric patients and young adults without statin exposure and those with a chronic myopathy resembling limb-girdle muscular dystrophy. HMGCR Ab Necrotizing autoimmune myopathy (NAM) HMGCR Antibodies Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal Necrotizing autoimmune myopathy (NAM) is a serious but rare muscle disease strongly associated with autoantibodies to either signal recognition protein (SRP) or 3-hydroxy-3-methylglutaryl-CoA reductase (HMGCR).

As a single case report, the presented clinical and laboratory findings can only be considered hypothesis generating. Statins and myositis: the role of anti-HMGCR antibodies Muscle toxicity is a recognized adverse effect of statin use. Recently, a new myositis syndrome was described in association with antibodies directed against the pharmacologic target of statins, anti-3-hydroxy-3-methylglutaryl-coenzyme A reductase (anti-HMGCR antibody). HMGCR Antibody (PA5-37367) in WB Western blot analysis of HMGCR in extracts of various cells using HMGCR polyclonal antibody (Product # PA5-37367).
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Cat.No. 13533-1-AP. Antibody information for antibodies HPA008338 and CAB016797 used in analysis of ENSG00000113161 / HMGCR () We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. HMGCR gene product.

This target gene encodes the protein '3-hydroxy-3-methylglutaryl-CoA reductase' in HPA008338 Sigma-Aldrich.
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Antigen synonymer, LDLCQ3,HMG CoAR,HMG-CoA reductase,3H3M,HMDH,3 hydroxy 3 methylglutaryl Coenzyme A reductase,Hmgcr,3 hydroxymethylglutaryl

2017-10-09 · Anti-HMGCR Antibody (C-1): sc-271595 Anti-HMGCR Antibody (C-1) is a mouse monoclonal IgG 1 κ HMGCR antibody, cited in 37 publications, provided at 200 µg/ml raised against amino acids 589-888 mapping at the C-terminus of HMGCR of human origin Anti-HMGCR Antibody (C-1) is recommended for detection of Monoclonal Anti-HMGCR antibody produced in mouse Prestige Antibodies ® Powered by Atlas Antibodies, clone CL0260, purified immunoglobulin, buffered aqueous glycerol solution human immunohistochemistry, western blot Rabbit polyclonal HMGCR (phospho S872) antibody.